Pardis Sabeti

For this systems biologist, the interaction of science and music is multiplicative.

Pardis Sabeti

[extra:Audio]

Listen to songs by Pardis Sabeti

On a recent Tuesday afternoon, Pardis Sabeti was not in her office at Harvard’s Center for Systems Biology, but en route to Manhattan—to play a gig that night at a club in the Meatpacking District with Thousand Days, the alternative-rock band for which she sings lead vocals and plays bass guitar. Though such weeknight gigs are rare and Sabeti admits she would choose science over music if pressed, the latter does not detract from her duties as assistant professor of organismic and evolutionary biology; the interaction, she says, is multiplicative, not subtractive. She keeps a guitar in her office to capture the songs that sometimes spill over during spells of scientific creativity. It was during just such a bout of “flow” that Sabeti made a landmark discovery in genetics. As a Rhodes scholar at Oxford in 2000, she was investigating a basic tenet of the field—that evidence of natural selection should be detectable on the human genome because beneficial variants spread quickly through populations. Many were searching for a way to find this evidence in the new data made available by genome sequencing; Sabeti was the first to devise a method, and her algorithm is now used routinely to identify areas of interest on the genome for further study. It was also at Oxford that she taught herself to play the guitar so she could help friends form a band. Aside from dabbling in piano lessons as a child, she had never before played an instrument, but, she says, she had been listening to music for so long that playing and writing followed naturally. In music and biology, experience has taught her, “If you do what you really love—find your passion—it comes easily.”

You might also like

‘passengers’ at A.r.t. Blends Acrobatics with Einstein’s Relativity

Review: Quantum mechanics meets circus arts at the American Repertory Theater’s performance

Bringing Korean Stories to Life

Composer Julia Riew writes the musicals she needed to see.

Thomas Andrew “Tom” Lehrer

The mathematician and satirist kept Harvard in his thoughts—and lyrics.

Most popular

At Harvard, Mike Pence Discusses Democracy and Conservatism

The former vice president denounces political violence, expresses hope for a deal between Trump and the University.

Harvard Art Historian Jennifer Roberts Teaches the Value of Immersive Attention

Teaching students the value of deceleration and immersive attention

Two Years of Doxxing at Harvard

What happens when students are publicly named and shamed for their views?

Explore More From Current Issue

Room filled with furniture made from tightly rolled newspaper sheets.

A Paper House in Massachusetts

The 1920s Rockport cottage reflects resourceful ingenuity.

James Muller in white lab coat leaning on railing in hospital hallway.

Free Speech, the Bomb-and Donald Trump

A Harvard cardiologist on the unlikely alliances that shaped a global movement to prevent nuclear war

Johnston Gate

Your Views on Harvard’s Standoff, Antisemitism, and More

Readers comment on the controversial July-August cover, authoritarianism, and scientific research.