What Ails You

What transpires at the frontiers of medicine? An astonishing array of health-related research is under way in the Boston biomedical complex, including laboratories at Harvard Medical School, its affiliated hospitals, the School of Public Health, and the Faculty of Arts and Sciences, which together comprise one of the nation's centers of such work. But a quick review of the "studies" listings in the "Calendar" section of a recent Harvard University Gazette, wherein volunteers are sought for human experiments and clinical trials, gives some hint of what is currently on investigators' minds. Herewith, an alphabetical selection from among three dozen-plus current probes of the body and mind.

Boston Communication and Health Study. Researchers seek African-American and European-American men and women ages 18-45 for a study of interpersonal communication style and blood pressure. The simple, noninvasive study involves a single visit that lasts approximately two and a half hours and offers a $35 stipend.

Child-rearing and Testosterone in Fathers Study. Researchers seek men with children younger than 1 year for a study on testosterone. Subjects should participate significantly in childcare. The study requires only eight saliva samples over two days to be taken in the subject's home. The procedure is not invasive and does not require experimenters to come to the subject's house. Subjects receive $25 for participation.

Craving Study. Researchers seek subjects between the ages of 18 and 65 who smoke, drink alcohol, or gamble and have at least once considered quitting or cutting down on these behaviors. Participation involves brain imaging, a physical examination, and three two-hour sessions over a two-week period. Participants receive $200 in gift certificates.

Estrogen Study. Researchers seek nonsmoking, post-menopausal women to participate in a study aimed at understanding the effects of estrogen on blood-vessel function. Compensation available.

Irritable Bowel Syndrome Study. Researchers seek subjects with Irritable Bowel Syndrome for a study testing an investigational drug. It is a placebo-controlled study with a one-in-five chance of receiving a placebo (sugar pill) instead of the investigational drug.

St. John's Wort Study. Researchers seek mild to moderately depressed individuals to participate in a study of St. John's Wort. Study involves only herbal medication. Compensation in the form of free St. John's Wort available after completion of study.

Sixth Sense/Very Shy Study. Researchers seek right-handed people who believe they have ESP, telepathy, or a "sixth sense"; often mistake noises for voices; sense the presence of others when alone; have extreme anxiety or discomfort in social situations involving unfamiliar people; and have very few close friends. Earn up to $200.

If you qualify, or wish to explore other opportunities to participate, the Gazette is available on the Internet at www.news.harvard.edu/gazette.

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